> ## Documentation Index
> Fetch the complete documentation index at: https://primerlab-genomic.mintlify.site/llms.txt
> Use this file to discover all available pages before exploring further.

# Concepts

# Concepts

Understanding how PrimerLab works.

## Architecture

* [System Architecture](architecture.md) — Three-tier design
* [Primer Design Logic](primer-design.md) — How Primer3 integration works
* [Quality Control](quality-control.md) — Tm, GC%, dimers, hairpins
* [Specificity Analysis](specificity.md) — Off-target detection and in-silico PCR

## Why Read This?

These pages explain the *why* behind PrimerLab's design decisions. Understanding these concepts helps you:

* Interpret results more effectively
* Troubleshoot design failures
* Customize parameters appropriately
* Integrate PrimerLab into your pipelines
